Thando Mpushe obtained his Post graduate Diploma in Opera at the University of Cape Town under Dr Brad Liebl and Kamal Khan. He has appeared in numerous roles including Harasta in Cunning Little Vixen, Trombonok in Il Viaggio a Reims, Marcelo in La Boheme by G. Puccini.

In 2012 he sang Poeta in Donizetti's Le Convenienze ed Inconvenienze Teatrali staged by the Richard Wagner Society of Cape Town.  Later that year he joined the Cape Town Opera Voice of the Nation Vocal Ensemble participating in numerous productions domestic and abroad.